WebSep 27, 2024 · Depletion of CTCF in cultured cells has minor effects on transcription … WebIdentification of these loops is a critical part of most Hi-C analyses. However, current …
Did you know?
WebSep 27, 2024 · Depletion of CTCF in cultured cells has minor effects on transcription whereas its mutation leads to embryonic lethality and developmental defects. In a recent issue of Nature Cell Biology, Soochit et al. (2024) show that the residence time of CTCF on DNA may explain its critical role in cell differentiation. http://www.biology.emory.edu/research/Corces/assets/a-ctcf-code-for-3d-genome-architecture.pdf
WebJul 11, 2024 · 1 Department of Biology, Emory University, 1510 Clifton Rd. NE, Atlanta, GA 30322, USA. ... Sperm- or oocyte-specific interactions mediated by CTCF and cohesin are only present in the paternal or maternal chromosomes, respectively, in the zygote and 2-cell stages. These interactions converge in both chromosomes by the 8-cell stage. WebJun 1, 2024 · The multidomain CCCTC-binding factor (CTCF), containing a tandem array of 11 zinc fingers (ZFs), modulates the three-dimensional organization of chromatin. We crystallized the human CTCF DNA-binding domain in …
WebMar 9, 2024 · 1 Department of Biology, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA. ... (CTCF)/cohesin binding sites in pluripotent cells. Elimination of hemimethylation causes reduced frequency of chromatin interactions emanating from these sites, suggesting a role for hemimethylation as a stable epigenetic mark regulating CTCF … WebMaintenance of CTCF and transcription factor ... - Emory University
WebSearch Results for all work with filters: Cell; Biology; Work 1-2 of 2. Sorted by relevance. Article CTCF: Master Weaver of the Genome. by Jennifer E. Phillips; Victor Corces 2009
WebJun 26, 2009 · CTCF is a highly conserved zinc finger protein implicated in diverse regulatory functions, including transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation. Here we re-evaluate data supporting these roles in the context of mechanistic insights provided by recent … eagle horn d2csi swindonWeb5.1 CTCF genome organizer and the cohesin complex. CTCF (CCCTC-binding factor) is … eagle hoops doncasterWebMolecular Cell Short Article Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA HideharuHashimoto,1,4 DongxueWang,1,4 JohnR.Horton,1,2 XingZhang,1,2 VictorG.Corces,3 andXiaodongCheng1,2,5,* 1Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road NE, Atlanta, GA 30322, USA … eagle hoo cottage rosemary beachWebProvider: Emory University Libraries Database: OpenEmory Content: text/plain; charset="utf-8" TY - JOUR TI - Is developmental synchrony enabled by CTCF residence time? csi synod pastoral concernsWebWe want to empower families and patients with knowledge about CTCF-Related Disorder … We are a team at Emory University that is searching for answers to help us … © Emory CRD Center CTCF-Related Diseases Center Gabriela Valverde de Morales, MD, MMSc Research Coordinator Emory CRD … Emory University, School of Medicine. 1365 Clifton Rd NE, Building B, Suite 2200. … Emory CRD Center. We are a team at Emory University that is searching for … [email protected]. Website ctcfemory.com. It doesn’t matter f you are a person with … Emory CRD Center. We are a team at Emory University that is searching for … CTCF and other architectural proteins, such as cohesin and TFIIIC, maintain genome … eagle hooksWebDrosophila CTCF tandemly aligns with other insulator ... - Emory University csisyncclient.exe record keyboard input