Cub domain-containing protein

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August undefined, 2024

WebMar 23, 2024 · The structure of CUB domains consists of a beta-sandwich with a jelly-roll fold. Almost all CUB domains contain four conserved cysteines that probably form two … WebMay 5, 2024 · We here demonstrate that the CUB-like-domain containing protein RBT-1 acts as a functional receptor of Cry6A, which mediates the intestinal cell interaction and …

WO/2024/084319 ANTIBODIES AGAINST CDCP1 FOR THE …

WebSummary. This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. WebNational Center for Biotechnology Information how does insulin work with glucose

Functional Role of Cell Surface CUB Domain-Containing Protein …

WebJul 27, 2011 · CUB and sushi domain-containing protein 1. Gene. Csmd1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mus musculus (Mouse) Amino acids. 3564. Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. Feature viewer. Publications. External links. History. BLAST Align. Download. Add Add a publication … WebJan 7, 2024 · Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a member of a small family of multifunctional cell surface-anchored glycoproteins functioning as co-receptors for a variety of growth factors. ... Ugef, and Bmp1 (CUB)-epidermal growth factor (EGF)-like domain-containing (SCUBE) protein family comprises three related … WebOct 3, 2024 · Abstract. Rationale: An antibody-drug conjugate (ADC) is a targeted therapy consisting of a cytotoxic payload that is linked to an antibody which targets a protein … how does insurance business work

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Q6NZL8 - UniProt

WebDec 13, 2024 · Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ... XM_047418383.1 → XP_047274339.1 signal peptide, CUB and EGF-like domain-containing protein 3 isoform X4. XM_047418382.1 → XP_047274338.1 signal peptide, CUB and EGF-like domain … WebSep 7, 2024 · The mature protein contains 2 putative CUB domains, a consensus type-1 palmitoylation motif, and 5 PxxP motifs that mediate binding to Src (190090) homology-3 domains. Northern blot analysis detected highest expression of a 6.0-kb transcript in skeletal muscle and colon, with lower expression in kidney, small intestine, placenta, and … how does insulin work to lower blood sugarWebDec 7, 2004 · PTHR24251:SF37 CUB DOMAIN-CONTAINING PROTEIN 2 1 hit; PTHR24251 OVOCHYMASE-RELATED 1 hit; PROSITE. View protein in PROSITE; PS01180 CUB 3 hits; Pfam. View protein in Pfam; PF00431 CUB 3 hits; SMART. View protein in SMART; SM00042 CUB 3 hits; SUPFAM. SSF49854 Spermadhesin, CUB … how does insurance adjuster work

"WebMar 2, 2015 · The transmembrane glycoprotein, CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein 1 (CDCP1) is overexpressed in several cancer types and is a predictor of poor … " - Cub domain-containing protein

Cub domain-containing protein

WebSep 1, 2009 · CUB and sushi domain-containing protein 3. Alternative names. CUB and sushi multiple domains protein 3; Gene names. Name. CSMD3. Synonyms. KIAA1894. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. Taxonomic lineage. WebDec 9, 2010 · Using such approaches, we identified CUB-domain–containing protein 1 (CDCP1) as a membrane protein that is up-regulated in highly metastatic melanomas. …

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WebOct 2, 2024 · Comment: annotation includes both PSPI/PSPII interaction residues highlighted. Download Cn3D for Viewing 3D Structure Scroll to Sequence Alignment … WebCUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix degradation during tumor invasion and metastasis in a tyrosine phosphorylation-dependent manner.

WebJun 14, 2010 · CUB domain–containing protein 1 (CDCP1) is a membrane protein that is highly expressed in several solid cancers. We reported previously that CDCP1 regulates … WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and …

WebJul 10, 2012 · The deduced 993-amino acid protein has an N-terminal signal sequence, followed by 9 putative calcium-binding EGF-like repeats, a spacer region, and a C-terminal CUB domain. The spacer region contains 5 potential N-glycosylation sites. SCUBE3 was predicted to be secreted as a mature 971-amino acid protein with a calculated molecular … WebMay 5, 2024 · elegans CUB-like-domain containing protein RBT-1, released by phosphatidylinositol-specific phospholipase C (PI-PLC), was identified as a Cry6Aa binding protein by affinity chromatography. RBT-1 contained a predicted glycosylphosphatidylinositol (GPI) anchor site and was shown to locate in lipid rafts in the …

WebMar 28, 2011 · Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is a secreted glycoprotein that is overexpressed in lung cancer tumor tissues and is correlated with the invasive ability in a lung ...

WebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological conditions and healthy women and in a number of other cancer … how does insurance calculate acvWebMar 29, 2024 · CUB domain-containing protein 1 (CDCP1) is a substrate of Src family kinases and has been shown to regulate anoikis resistance, migration and matrix … how does insurance change with rentersWebDec 9, 2010 · CDCP1 Is Up-Regulated in Highly Metastatic Melanoma Cell Lines. CDCP1, also known as SIMA135 or Trask, is a transmembrane glycoprotein that contains three putative extracellular CUB domains. CUB domains are believed to function in protein–protein ( 22, 23) and protein/carbohydrate ( 24) interactions. We initially … photo moutonsWebLaw, M. E., Ferreira, R. B., Davis, B. J., Higgins, P. J., Kim, J.-S., Castellano, R. K., … Law, B. K. (2016). CUB domain-containing protein 1 and the epidermal ... how does insurance companies create valueWebAbstact. To measure the levels of serum CUB and zona pellucida-like domain-containing protein 1 (CUZD1) in patients with ovarian cancer (OvCa), benign gynecological … how does insurance claims workWebMay 21, 2024 · CUB domain-containing protein-1 (CDCP1) is a transmembrane protein that contains three extracellular CUB domains and acts as a substrate for Src family … how does insulin work in your bodyWebMay 21, 2024 · The role of CDCP1 (CUB domain-containing protein 1) and ADAM12 (a disintegrin and metalloproteinase 12) in ovarian cancer. J BUON. 2015;20(3):673–679. 16. Miura S, Hamada S, Masamune A, et al. CUB-domain containing protein 1 represses the epithelial phenotype of pancreatic cancer cells. how does insurance company earn money