Early endosome antigen 1

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August undefined, 2024

WebEarly endosome antigen 1 (EEA1) is a 170 kDa coiled-coil protein belonging to a group of early endosomal Rab5 effector proteins. EEA1 has a putative role in the tethering/docking of endocytic vesicles prior to their fusion with early endosomes. This protein is characterized as containing a zinc finger-like domain and coiled-coil regions. WebAutoantibodies to EEA1, an antigen on early endosomes, were first reported in the serum of a patient with subacute cutaneous lupus erythematosus (SCLE). Here we have …

EEA1 Antibody (E-8) SCBT - Santa Cruz Biotechnology

WebMay 15, 2015 · Following entry into host cells, OMVs migrate to early endosome antigen 1 (EEA1)-labelled endosomes where they interact with and are detected by nucleotide-binding oligomerization domain ... WebSep 17, 2024 · The crucial effectors of Rab5 are early endosome antigen-1 (EEA1) [28, 29], rabaptin-5 [30, 31, 37], rabenosyn-5 [32, 38], APPL1/2 [33, 34], and ZFYVE21 (Table 1). EEA1, a key effector of Rab5 with a molecular weight of 162 kD, is a biomarker for early endosomes and has a parallel coiled-coil homodimer structure. cisco bandwidth analysis

Early Endosome Antigen 1 - an overview ScienceDirect …

WebJan 3, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast … WebMar 5, 2024 · EEA1 early endosome antigen 1 [Homo sapiens (human)] - Gene - NCBI NCBI Skip to main content Skip to navigation Resources All Resources Chemicals & … WebRab22a is an important small GTPase protein the molecule that is involved in intracellular transportation and regulation of proteins. It also plays an important role in antigens uptake, transportation, regulation of endosome morphology, and also regulates the transport of antigens to MHC (Major Histocompatibility Complex) molecules. To investigate the role … cisco bangalore careers

EEA1 Polyclonal Antibody, Invitrogen 100 μg; …

The FYVE domain of early endosome antigen 1 is required for bot…

WebEea1 early endosome antigen 1 [ (house mouse)] Gene ID: 216238, updated on 8-Nov-2024 Summary Predicted to enable 1-phosphatidylinositol binding activity; GTP … cisco bandwidth 10000WebEEA1, early endosome antigen 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog EEA1, early endosome antigen 1. … diamond race car chassis brownstown indiana

"WebNov 29, 2016 · Early endosome antigen-1 and Ras-related protein-11 expressions were upregulated; however, the localized distributions of these pivotal proteins were altered. We hypothesized that these LVLS were held by the internalized and dispersed particles decreasing the amount of cell membrane available to support the completion of cytokinesis. " - Early endosome antigen 1

Early endosome antigen 1

WebThe gene Early Endosome Antigen 1 (EEA1) encodes for around 1400 amino acid proteins. It is a peripheral membrane protein associated with the cytoplasmic face of early endosomes. EEA1 is a autoantigen associated with subacute cutaneous systemic lupus erythematosus and is a coiled-coil protein localized to early endosomes and cytosol. WebEarly Endosome Antigen 1. In the case of the EEA1 FYVE domain, the emission of a single conserved tryptophan residue located in the head group binding site is quenched …

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WebEEA1, early endosome antigen 1 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog EEA1, early endosome antigen 1. Synonyms MST105, MSTP105, ZFYVE2 Links HGNC:3185. NCBI Gene ID: 8411. neXtProt AC: NX_Q15075. UniProt: Q15075. Chr Location ... WebApr 27, 2024 · Therefore, we, co-transfected cells with the well-known tethering protein early endosome antigen 1 (EEA1) tagged to GFP (EEA1-GFP) (Bergeland et al., 2008; …

WebFeb 1, 2004 · Rab5 together with early endosome antigen 1 (EEA1) 118,119,120 — a phosphoinositide-binding protein — regulate fusion between primary endocytic vesicles and sorting endosomes. More … WebJul 10, 2024 · At this stage, ingested materials can be recycled back to the plasma membrane, sent to the trans-Golgi Network (TGN), or degraded through endosomal acidification. Each compartment in the pathway is marked by characteristic proteins, such as early endosome antigen 1 (EEA1), lysosomal-associated membrane protein 1 …

WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … WebSep 2, 2005 · The FYVE domain is defined by the three conserved elements: the N-terminal WxxD, the central RR/KHHCR, and the C-terminal RVC motifs that form the PtdIns(3)P binding site seen in the solution and crystal structures of early endosome antigen 1 (EEA1), Hrs, and Vps27p FYVE (6, 13, 17, 18).The PtdIns(3)P headgroup is coordinated …

WebJul 9, 2024 · The derived amino acid sequence was found to be 99% identical to a 180 kd peripheral endosomal protein named early endosome antigen (EEA1). Results: …

WebEarly endosome antigen 1 (EEA1) is 170-kDa polypeptide required for endosome fusion. EEA1 binds to both phosphtidylinositol 3-phosphate (PtdIns3P) and to Rab5-GTP in … diamond q veterinary clinic fargo ndWebEEA1 Antibodies. Antibodies that detect EEA1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … cisco bad gatewayWebEarly endosomes are a major cytoplasmic sorting compartment from which receptors and ligands may be distributed to various sites within the cell. Early endosome antigen 1 (EEA1) is a 180 kDa hydrophilic peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence studies show that EEA1 colocalizes to early … diamond r accessories for can am spyderWebView Assessment - Lecture 4.6 Antigen processing.pdf from BIOL 310 at Nazarbayev University. Learning goals Antigen processing 1. To draw both pathways of antigen processing and presentation of cisco bandwidth qos-referenceWebOct 1, 2013 · Early endosome antigen 1 (EEA1) is a peripheral membrane protein present in cytosol and membrane fractions. Immunofluorescence staining of EEA1 in macrophage cells yields punctuate staining pattern consistent with the cytoplasmic distribution of endosomes, but in a different way when compare uninfected-macrophages ( Fig. 2A ) in … diamond quilted short padded jacketWebDec 14, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains … diamond races isle of wightWebEndosomes are found in three forms: early endosomes, late endosomes, and recycling endosomes. The early endosomes develop into late endosomes, which then fuse with … cisco bang and olufsen