WebThe H (+)-K (+)-ATPases are ion pumps that use the energy of ATP hydrolysis to transport protons (H (+)) in exchange for potassium ions (K (+)). These enzymes consist of a … Web10 gen 2024 · Die H + /K +-ATPase ist eine heterodimeres Protein, das von 2 Genen kodiert wird. Das ATP4A-Gen kodiert die α-Untereinheit. Dabei handelt es sich um ein Protein …
The renal H,K-ATPases - PubMed
Web1 giu 1999 · The Na-K/H-K-ATPase gene family is divided in three subgroups including the Na-K-ATPases, mainly involved in whole body and cellular ion homeostasis, the gastric H-K-ATPase involved in gastric fluid acidification, and the newly described nongastric H-K-ATPases for which the identification of physiological roles is still in its infancy. The first … Web25 nov 2008 · The gastric H,K-ATPase is the primary target for the treatment of acid-related diseases. Proton pump inhibitors (PPIs) are weak bases composed of two moieties, a substituted pyridine with a primary pKa of about 4.0, which allows selective accumulation in the secretory canaliculus of the parietal cell, and a benzimidazole with a second pKa of … free way to call
Biomolecules Free Full-Text Plasma Membrane Ca2+–ATPase in …
Web22 apr 2010 · 1 Introduction. The mammalian Na +,K +-ATPase (NKA) and H +,K +-ATPase (HKA) maintain key ionic imbalances between cells and their surroundings by exporting sodium ions and protons, respectively, in exchange for potassium ions.These gradients provide the driving force for numerous cellular functions, e.g. for establishing the … WebExplore the latest full-text research PDFs, articles, conference papers, preprints and more on CDNA CLONING. Find methods information, sources, references or conduct a literature review on CDNA ... WebDie Protonen-Kalium-Pumpe oder H + /K +-ATPase ist ein Enzym in den Belegzellen im Magen, das den Transport von Protonen aus den Zellen heraus und gleichzeitig von Kaliumionen in die Zelle hinein bewerkstelligt. Dabei wird ATP verbraucht, es handelt sich also um eine so genannte membranständige ATPase.Werden von der Zelle nun noch … fashionfull co kr